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Guideline Development

Our team brings extensive experience developing evidence-based clinical practice guidelines. 


As INGUIDE Certified Guideline Methodologists, we use rigorous, transparent methods and an evidence-to-decision framework to develop practical recommendations for health and healthcare decisions. 


Alongside the research evidence, we consider the values and preferences of those affected by the recommendations, as well as equity, feasibility and acceptability considerations.


We bring expertise across the full guideline development process, including:

  • Leading evidence reviews to identify, synthesize, and critically appraise the available evidence
  • Developing GRADE Evidence-to-Decision (EtD) frameworks to support transparent, evidence-informed recommendations
  • Managing panel voting and consensus processes to facilitate structured, transparent decision-making
  • Engaging people with lived experience to ensure guidelines reflect the perspectives, priorities, and needs of those most affected.


Our Guideline Work

  • Canadian Guidelines for Post COVID-19 Condition
  • CRA living guidelines for the pharmacological management of rheumatoid arthritis with disease-modifying anti-rheumatic drugs.  April 2026 
  • Canadian Rheumatology Association/Spondyloarthritis Research Consortium of Canada Living Guideline for the Management of Axial Spondyloarthritis. April 2026 
  • CRA/CanRIO guidelines for the management of baseline immunosuppression in individuals with pre-existing rheumatic diseases initiating immune checkpoint inhibitors. September 2025 
  • Operationalizing the GRADE-equity criterion to inform guideline recommendations: application to a medical cannabis guideline. Journal of Clinical Epidemiology, January 2024
  • Guidelines for the treatment of human African trypanosomiasis. WHO. 2024 
  • The CRA living guidelines for the Screening, Monitoring and Treatment of Juvenile Idiopathic Arthritis-Associated Uveitis. October 2022 
  • CRA Recommendation on Three Doses of mRNA Vaccine for Preventing COVID-19.  November 2021 
  • Updated CRA Recommendation on COVID-19 Vaccination in Persons with Autoimmune Rheumatic Disease. November 2021 
  • Clinical guideline for homeless and vulnerably housed people, and people with lived homelessness experience. Pottie et al. 2020 (CMAJ)
  • Canadian Rheumatology Association Recommendations for the Assessment and Monitoring of Systemic Lupus Erythematosus. The Journal of Rheumatology, September 2018 
  • Public health guidance on screening and vaccination for infectious diseases in newly arrived migrants within the EU/EEA. European Centre for Disease Prevention and Control, 2018
  • WHO recommendations on home-based records for maternal, newborn and child health. World Health Organisation, 2018

Projects in progress

  • Canadian Urticaria Guidelines
  • Canadian Morphea Guidelines
  • Cancer Detection Guidelines and Resources for Firefighters in Canada


Other Guideline-related Work

  • WHO guidelines on leishmaniases: Treatment of visceral leishmaniasis and post-kala-azar dermal leishmaniasis in eastern Africa and South-East Asia. WHO. 2026.
  • Abortion care guideline, second edition. WHO. 2025
  • Guidelines for the treatment of human African trypanosomiasis. WHO. 2024 
  • WHO guideline for the treatment of visceral leishmaniasis in HIV co-infected patients in East Africa and South-East Asia. WHO. 2022

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